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Bringing Powerful New Technologies to the Clinical Lab
Over the past decade, major advances have been made in molecular diagnostic testing for infectious diseases. Many of those advances originated in the research laboratories of Gen-Probe, and have changed the basic methods of operation in microbiology laboratories around the world.
Compared to traditional methods, molecular genetic assays offer better performance and shorter testing times. Most of all, clinicians are now able to provide patients and the community with more consistent, affordable, and higher-quality healthcare.
Gen-Probe's research efforts over the last 15 years have led to the development of five core technologies:
Ribosomal RNA (rRNA) Targeting
Gen-Probe patented the use of rRNA as a target molecule, which results in nucleic acid probe assays with increased sensitivity and specificity.
Target Capture (TC)
Uses oligonucleotides and magnetic microparticles to isolate target nucleic acid for amplification and eliminate potentially inhibiting substances.
Transcription-Mediated Amplification (TMA)
TMA is a transcription-based nucleic acid amplification technology that amplifies target RNA or DNA sequences a billion fold within 15-30 minutes.
Hybridization Protection Assay (HPA)
Uses a specific DNA probe that hybridizes with nucleic acid target amplicon to emit a chemiluminescent signal.
Dual Kinetic Assay (DKA)
Extends the power of HPA and TMA by enabling the simultaneous detection of two analytes.
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2008 Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121
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