Transfusion Medicine

LIFECODES Pak Family Products

Platelets express glycoproteins that are polymorphic and can become the targets for antibody responses.  Detecting these antibodies offers the clinician the potential to better identify compatible blood products and improve patient care.

LIFECODES Pak Family Products
The Pak family of products provide well-characterized platelet glycoproteins immobilized either directly and/or captured by monoclonal antibodies to the wells of a microwell plate.  The available formats allow a user to detect antibodies that bind to the platelet-specific glycoproteins (IIb/IIIa, Ib/IX, Ia/IIa and IV) and Class I HLA.1,2,3,4,5

PakAuto has been designed to detect autoantibodies to patient glycoproteins.  These antibodies are eluted from the patient’s own platelets or found circulating in plasma.6

  • Kits available for both allo and auto platelet antibody detection
  • Differentiate HLA from platelet antibodies
  • Multiple kit formats allow for maximum flexibility

1 LIFECODES PakPlus for in vitro diagnostic use [package insert], Waukesha, WI; Gen-Probe GTI Diagnostics, Inc., 2011.
2 LIFECODES Pak12 for in vitro diagnostic use [package insert], Waukesha, WI; Gen-Probe GTI Diagnostics, Inc., 2011.
3 LIFECODES Pak12G for in vitro diagnostic use [package insert], Waukesha, WI; Gen-Probe GTI Diagnostics, Inc., 2011.
4 LIFECODES Pak1 for in vitro diagnostic use [package insert], Waukesha, WI; Gen-Probe GTI Diagnostics, Inc., 2011.
5 LIFECODES Pak2-LE for in vitro diagnostic use [package insert], Waukesha, WI; Gen-Probe GTI Diagnostics, Inc., 2011.
6
LIFECODES PakAuto for in vitro diagnostic use [package insert], Waukesha, WI; Gen-Probe GTI Diagnostics, Inc.,
2011.

DescriptionQuantityCatalog
LIFECODES PakPlus
Designed to detect antibodies to HLA class I antigens and to epitopes on the platelet glycoproteins IIb/IIIa, Ib/IX, Ia/IIa, and IV.
5 Tests/Kit PAKPLUS
LIFECODES Pak12
Designed to detect antibodies to HLA class I antigens and to epitopes on the platelet glycoproteins IIb/IIIa, Ia/IIa, and Ib/IX.
5 Tests/Kit PAK12
LIFECODES Pak12G
Designed to detect IgG antibodies to HLA class I antigens and to epitopes on the platelet glycoproteins IIb/IIIa, Ia/IIa, and Ib/IX.
5 Tests/Kit PAK12G
LIFECODES Pak1
Designed to detect platelet-specific antibodies reactive with epitopes on platelet glycoprotein IIb/IIIa.
5 Tests/Kit PAK1
LIFECODES Pak2-LE
Designed to detect IgG antibodies to HLA class I antigens and to epitopes on the platelet glycoproteins IIb/IIIa, Ia/IIa, and Ib/IX.
11 Tests/Kit PAK2-LE
LIFECODES PakAuto
Designed to detect platelet autoantibodies eluted from patient's platelets or circulating in the patient's serum or plasma.
5 Tests/Kit PAKAUTO
Cat #ProductTests/KitPI
PAKPLUS LIFECODES PakPlus 5 SS ESS
PAK12 LIFECODES Pak12 5 SS ESS
PAK12G LIFECODES Pak12G 5 SS ESS
PAK1 LIFECODES Pak1 5 SS ESS
PAK2-LE LIFECODES Pak2-LE 11 SS ESS
PAKAUTO LIFECODES PakAuto 5 SS ESS


Stopping Solution Codes
SS: NaOH Stopping Solution
ESS: New Stopping Solution

Please check the Stopping Solution symbol on the product label to select the correct package insert.

Cat #ProductTests/KitMSDS
PAKPLUS LIFECODES PakPlus 5 MSDS
PAK12 LIFECODES Pak12 5 MSDS
PAK12G LIFECODES Pak12G 5 MSDS
PAK1 LIFECODES Pak1 5 MSDS
PAK2-LE LIFECODES Pak2-LE 11 MSDS
PAKAUTO LIFECODES PakAuto 5 MSDS

PakPlus, Pak12, Pak12G, Pak1, Pak2-LE and PakAuto products are cleared for In Vitro Diagnostic Use by the FDA.

For additional availability in other countries please contact your local sales representative or distributor.

 

Technical Bulletins are now available on the Downloads Tab

Cat #ProductTests/KitDocument
PAKPLUS LIFECODES PakPlus 5 Recording Sheet
PAK12 LIFECODES Pak12 5 Recording Sheet
PAK12G LIFECODES Pak12G 5 Recording Sheet
PAK1 LIFECODES Pak1 5 Recording Sheet
PAK2-LE LIFECODES Pak2-LE 11 Recording Sheet
PAKAUTO LIFECODES PakAuto 5 Recording Sheet