GASDirect Test

The Hologic Gen-Probe GASDirect Test for Group A Streptococcus is a DNA probe assay which uses nucleic acid hybridization for the qualitative detection of Group A Streptococcal RNA directly from throat swabs with high sensitivity and specificity. This direct probe eliminates the time and difficulty of culturing Group A Streptococci. Further, the 2000 edition of the American Academy of Pediatrics Red Book recommends that all negative rapid antigen assays be backed up by culture or a test that is equivalent to culture. Hologic Gen-Probe's GASDirect Test can be used to back up the negative rapid antigen assays or as a stand alone test.

Features/Benefits:

  • Provides fast, accurate diagnosis - same day results vs. 2-3 days for culture
  • Higher sensitivity than rapid direct antigen tests
  • Accuracy equivalent to standard culture
  • User-friendly non-isotopic test format helps to reduce technician training
  • A study documented that Hologic Gen-Probe's GASDirect test is comparable to culture with respect to cost and assay performance, yet with an improved turn around time of 24 hours vs. 72 hours compared to culture.1
  • Streamlines workflow with a simple 3-step procedure
  • Enables batch testing
  • Decreases technician time
  • Automation options available for higher-volume labs

Since the signs and symptoms of viral and bacterial infections are broadly similar, accurately diagnosing these upper respiratory tract illnesses allows physicians to properly treat their patients without contributing to the further development of antibiotic resistant bacteria.

References:
1Chapin, K.C., P. Blake, and C.D. Wilson. 2002. Performance characteristics and utilization of rapid antigen test, DNA probe, and culture for detection of group A streptococcus in an acute care clinic. J. Clin. Microbiol. 40:4207-4210.

DescriptionQuantityCatalog
GASDirect Test
DNA probe assay which uses nucleic acid hybridization for the qualitative detection of Group A Streptococcal rRNA as an aid in the diagnosis of Group A Streptococcal pharyngitis from throat swabs.
100 tests
500 tests
103890
103890B
Hologic Gen-Probe Detection Reagent Kit
Detection reagent used on LEADER instruments for non-APTIMA branded Hologic Gen-Probe Assays.
1,200 tests 201791
Polypropylene Tubes
12 mm x 75 mm.
250 tubes per package 102440
Cat #ProductKit SizePI
103890 Group A Streptococcus Direct Test 100 tests PI
103890B Group A Streptococcus Direct Test 500 tests PI

To access current MSDS documents for this product, please go to the MSDS tab above, or 
click here and select the specific product information you need.

The GASDirect test was cleared for In Vitro Diagnostic Use by the FDA in 1994.

For additional availability in other countries please contact your local sales rep or distributor.

The within-run precision of the Hologic Gen-Probe GROUP A STREPTOCOCCUS DIRECT TEST was calculated by assaying two concentrations of ribosomal RNA isolated from Streptococcus pyogenes and a single concentration of S. pyogenes cells using 10 replicates in a single assay.

Gas Direct Performance Data

* Please see package insert for detailed information.

The between-run precision was calculated by assaying one concentration of Streptococcus pyogenes ribosomal RNA, and two suspensions of Streptococcus pyogenes per assay. Each of three operators ran one replicate in each of four separate runs.

Gas Direct Performance Data

* Please see package insert for detailed information.

A clinical reproducibility study was conducted at three sites using coded materials for inoculation onto swabs. All sites tested two coded swabs for each of the variables listed below. Two replicate hybridization assays were run on each swab.

Gas Direct Performance Data

Please see package insert for detailed information.