LIFECODES Pak Family Products
Platelets express glycoproteins that are polymorphic and can become the targets for antibody responses. Detecting these antibodies offers the clinician the potential to better identify compatible blood products and improve patient care.
LIFECODES Pak Lx
Luminex-based assay for the detection of antibodies to the most common epitopes on human platelet glycoproteins; Ia/IIa, IIb/IIIa, Ib/IX, GPIV and HLA Class I. It has been designed to detect IgG antibodies to Human Platelet Antigen (HPA) -1, -2, -3, -4, -5, GPIV and Class I HLA.
LIFECODES Pak Family ELISA Products
The Pak family of products provide well-characterized platelet glycoproteins immobilized either directly and/or captured by monoclonal antibodies to the wells of a microwell plate. The available formats allow a user to detect antibodies that bind to the platelet-specific glycoproteins (IIb/IIIa, Ib/IX, Ia/IIa and IV) and Class I HLA.1,2,3,4
PakAuto has been designed to detect autoantibodies to patient glycoproteins. These antibodies are eluted from the patient’s own platelets or found circulating in plasma.5
- Kits available for both allo and auto platelet antibody detection
- Differentiate HLA from platelet antibodies
- Multiple kit formats allow for maximum flexibility
1 LIFECODES PakPlus for in vitro diagnostic use [package insert], Waukesha, WI; Hologic Gen-Probe GTI Diagnostics, Inc., 2011.
2 LIFECODES Pak12 for in vitro diagnostic use [package insert], Waukesha, WI; Hologic Gen-Probe GTI Diagnostics, Inc., 2011.
3 LIFECODES Pak12G for in vitro diagnostic use [package insert], Waukesha, WI; Hologic Gen-Probe GTI Diagnostics, Inc., 2011.
4 LIFECODES Pak2-LE for in vitro diagnostic use [package insert], Waukesha, WI; Hologic Gen-Probe GTI Diagnostics, Inc., 2011.
5 LIFECODES PakAuto for in vitro diagnostic use [package insert], Waukesha, WI; Hologic Gen-Probe GTI Diagnostics, Inc., 2011.
| Description | Quantity | Catalogue |
|---|---|---|
| LIFECODES Pak Lx Designed to detect and differentiate between IgG antibodies to HPA-1, HPA-2, HPA-3, HPA-4, HPA-5, GPIV and Class I HLA in human serum. |
16 Tests/Kit | PLX |
| LIFECODES PakPlus Designed to detect antibodies to HLA class I antigens and to epitopes on the platelet glycoproteins IIb/IIIa, Ib/IX, Ia/IIa, and IV. |
5 Tests/Kit | PAKPLUS |
| LIFECODES Pak12 Designed to detect antibodies to HLA class I antigens and to epitopes on the platelet glycoproteins IIb/IIIa, Ia/IIa, and Ib/IX. |
5 Tests/Kit | PAK12 |
| LIFECODES Pak12G Designed to detect IgG antibodies to HLA class I antigens and to epitopes on the platelet glycoproteins IIb/IIIa, Ia/IIa, and Ib/IX. |
5 Tests/Kit | PAK12G |
| LIFECODES Pak2-LE Designed to detect IgG antibodies to HLA class I antigens and to epitopes on the platelet glycoproteins IIb/IIIa, Ia/IIa, and Ib/IX. |
11 Tests/Kit | PAK2-LE |
| LIFECODES PakAuto Designed to detect platelet autoantibodies eluted from patient's platelets or circulating in the patient's serum or plasma. |
5 Tests/Kit | PAKAUTO |
| Cat # | Product | Tests/Kit | PI |
|---|---|---|---|
| PLX | LIFECODES Pak Lx | 16 | EN FR DE IT ES PT |
| PAKPLUS | LIFECODES PakPlus | 5 | EN SS EN ESS DA SS DA ESS FR SS FR ESS DE SS DE ESS EL SS EL ESS IT SS IT ESS PT SS PT ESS ES SS ES ESS JA ESS TW |
| PAK12 | LIFECODES Pak12 | 5 | EN SS EN ESS DA SSDA ESS FR SSFR ESSDE SSDE ESS EL SSEL ESSIT SSIT ESS PT SSPT ESSES SSES ESS SV SSSV ESS |
| PAK12G | LIFECODES Pak12G | 5 | EN SS EN ESS FR SS FR ESS DE SS DE ESS EL SS EL ESS IT SS IT ESS PT SS PT ESS ES SS ES ESS |
| PAK1 |
LIFECODES Pak1 Discontinued |
5 | EN SS EN ESS DA SS DA ESS FR SS FR ESS DE SS DE ESS EL SS EL ESS IT SS IT ESS PT SS PT ESS ES SS ES ESS |
| PAK2-LE | LIFECODES Pak2-LE | 11 | EN SS EN ESS FR SS FR ESS DE SS DE ESS EL SS EL ESS IT SS IT ESS PT SS PT ESS ES SS ES ESS |
| PAKAUTO | LIFECODES PakAuto | 5 |
EN SS EN ESS FR SS FR ESS |
Stopping Solution Codes
SS: NaOH Stopping Solution
ESS: New Stopping Solution
Please check the Stopping Solution symbol on the product label to select the correct package insert.
| Cat # | Product | Tests/Kit | MSDS |
|---|---|---|---|
| PLX | LIFECODES Pak Lx | 16 | EN FR DE ES PT IT |
| PAKPLUS | LIFECODES PakPlus | 5 | EN FR DE ES PT |
| PAK12 | LIFECODES Pak12 | 5 | EN FR DE ES PT |
| PAK12G | LIFECODES Pak12G | 5 | EN FR DE ES PT |
| PAK1 | LIFECODES Pak1 Discontinued |
5 | EN FR DE ES |
| PAK2-LE | LIFECODES Pak2-LE | 11 | EN FR DE ES PT |
| PAKAUTO | LIFECODES PakAuto | 5 | EN FR DE ES |
Pak Lx, PakPlus, Pak12, Pak12G, Pak2-LE and PakAuto products are CE marked for IVD use.
PakPlus is For Research Use Only in Japan.
For additional availability in other countries please contact your local sales representative or distributor.
Technical Bulletins are now available on the Downloads Tab
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Technical Bulletins are now available on the Downloads Tab