Elucigene CF-EU2v1 Kits
The Elucigene CF-EU2v1 kit has been specifically developed and approved for in vitro diagnostic testing within Europe. The Elucigene CF-EU2v1 assay identifies 50 of the most frequently observed CFTR gene mutations within populations of European origin.
Key Benefits of using Elucigene CF-EU2v1 Kits:
- Developed specifically for testing European populations
- The only commercially available product that quantifies intron 8 TG repeat variance
- Poly T analysis can be switched on or off as required
- Detects wildtype and mutant alleles (i.e. full genotyping)
- Validated for use on Applied Biosystems’ 3100/3130/3500 Genetic Analyzers
- Results can be analysed using GeneMapper or GeneMarker software
- Customized GeneMarker application for simple patient analysis and reporting
Intron 8 poly T variants
The polymorphic thymidine tract at the junction of intron 8 and exon 9 of the CFTR gene influences transcription. It is well known that the number of thymidine residues (5T,7T or 9T) affects splicing efficiency of exon 9, if the 5T allele is present a proportion of exon 9 transcripts will be absent resulting in non-functional protein and variable CF symptoms. It is also reported that the number of TG repeats upstream of the polythymidine tract can aslo affect splicing of exon 9. If present on the same allele as the 5T variant the longer the number TG repeats the higher the proportion of CFTR transcripts will lack exon 9. The ability to identify the number of TG repeats in addition to poly T status can provide further valuable information to assist clinical magement of the patient. Both poly T status and the number of TG repeats can be determined using Elucigene CF-EU2v1.
GENEMAPPER is a trademark of Applied Biosystems, LLC.
GENEMARKER is a trademark of SoftGenetics.
This product is not approved by the FDA and is not available for sale in the US
| Description | Quantity | Catalogue |
|---|---|---|
|
Elucigene CF-EU2v1 |
50 test kit | CF2EUB2 |
| Cat # | Product | Kit Size | Instructions for Use |
|---|---|---|---|
| CF2EUB2 | Elucigene CF-EU2v1 | 50 tests |
EN CS DA DE EL ES FR IT LT NO PT SK Guide to Analysis EN CS DA DE EL ES FR IT LT NO PT SK Small Insertions & Deletions by Peak |
The neccessary analysis files and settings for GeneMarker and GeneMapper are provided below:
| GeneMapper 3.7 and above |
| GeneMapper settings |
| GeneMarker v1.95 |
| Cat # | Product | Kit Size | MSDS |
|---|---|---|---|
| CF2EUB2 | Elucigene CFEU2v1 | 50 tests | EN |
All CF-EU2v1 kits comply with the IVDD EC Directive 98/79/EC, carry the CE mark and are manufactured within quality systems accredited to ISO9001:2008 and ISO13485:2003. Full technical support is provided to purchasers of kits to ensure acceptable performance and customer satisfaction.
This product is not approved by the FDA and is not available for sale in the US.
For additional availability in other countries please contact your local sales rep or distributor.
For information on our Elucigene CF-EU2v1 product please download our brochure:
Click to Download
GENEMAPPER is a trademark of Applied Biosystems, LLC.
GENEMARKER is a trademark of SoftGenetics.